PRIDE Archive

PRIDE Archive: Advancing Proteomics Through Open Data Sharing

The PRIDE Archive represents a cornerstone in the proteomics research ecosystem, serving as a centralized repository for mass spectrometry-based proteomics data. This EBI-maintained resource ensures data accessibility, reproducibility, and reusability in proteomics research.

Core Functionalities

1. Data Submission Submission Features:

• ProteomeXchange integration
• Metadata validation
• File format checking
• Version control
• Dataset identifiers

2. Data Types Supported

• Raw MS data
• Peak lists
• Search results
• Protein identifications
• Quantification data
• Post-translational modifications

Key Features

1. Data Access Browse and Search:

• Project metadata
• Experimental details
• Protein identifications
• Dataset downloads
• API access

2. Quality Control Data Validation:

• Format compliance
• Metadata completeness
• Technical validation
• Search result validation
• Data consistency

Research Applications

1. Data Sharing

• Publication support
• Collaboration
• Method validation
• Result verification
• Meta-analysis

2. Data Analysis

• Protein identification
• PTM analysis
• Quantitative analysis
• Comparative studies
• Method development

3. Reuse Scenarios

• Meta-studies
• Method comparison
• Algorithm development
• Quality benchmarking
• Training datasets