PeptideAtlas: Mapping the Protein Universe
In the complex landscape of proteomics research, PeptideAtlas stands as a vital resource that compiles and reanalyzes mass spectrometry-based proteomics data to create a comprehensive view of organisms' proteomes.
Core Components
- Data Repository Content Types:
- Observed peptides
- Protein identifications
- MS/MS spectra
- Transition lists
- SRM assays
- PTM information
- Analysis Tools Built-in Features:
- BLAST search
- Peptide viewer
- Protein viewer
- SRMAtlas integration
- Statistical analysis
- Data visualization
Key Functionalities
- Data Access Search Options:
- Peptide sequences
- Protein identifiers
- Genomic coordinates
- Spectral libraries
- SRM transitions
- PTM patterns
- Research Tools Analysis Features:
- Proteome coverage
- Peptide uniqueness
- PTM mapping
- Transition selection
- Assay design
- Statistical validation
Applications
- Discovery Proteomics
- Proteome mapping
- PTM identification
- Protein validation
- Coverage analysis
- Method development
- Targeted Proteomics
- SRM assay design
- Transition selection
- Method optimization
- Validation studies
- Quantification strategies