MaxQuant: Transforming Proteomics Data Analysis
MaxQuant has established itself as an essential tool in the proteomics research community, providing researchers with sophisticated algorithms and user-friendly interfaces for processing complex mass spectrometry data.
Core Functions
- Data Processing Primary Features:
- Raw data analysis
- Peak detection
- Mass recalibration
- Peptide identification
- Protein quantification
- PTM analysis
- Quantification Methods Support for:
- Label-free quantification
- SILAC
- TMT/iTRAQ
- Label-based methods
- Absolute quantification
- XIC-based quantification
Key Capabilities
- Analysis Workflow Processing Steps:
- Raw file processing
- Feature detection
- Database searching
- Quantification
- Statistical analysis
- Result visualization
- Advanced Features Specialized Tools:
- Match-between-runs
- PTM scoring
- De novo sequencing
- Ion mobility support
- Cross-linking analysis
- Machine learning integration
Research Applications
- Discovery Proteomics
- Protein identification
- Expression analysis
- PTM mapping
- Interaction studies
- Biomarker discovery
- Targeted Analysis
- Selected reaction monitoring
- Multiple reaction monitoring
- Parallel reaction monitoring
- Peptide quantification
- Protein validatio