Dexmedetomidine as a Perioperative Adjunct in Valvular Cardiac Surgery

Background: Valvular heart surgery is associated with considerable perioperative risks including hemodynamic instability, arrhythmias, renal dysfunction and prolonged ICU stay. Dexmedetomidine a selective alpha 2-adrenoceptor agonist, provides sedation and sympatholysis and has been investigated as a cardioprotective adjunct. Objectives: To evaluate the effects of dexmedetomidine on intraoperative hemodynamic stability and postoperative outcomes in adult patients undergoing valvular replacement surgery. Methods: In this retrospective study, 154 patients who underwent valvular surgery under cardiopulmonary bypass between January 2022 and June 2023 were analyzed. Patients were divided into Gro