medRxiv preprint

Machine Learning and Explainable AI for Multi-State Classification of Malaria Transmission Dynamics in Kenya

Malaria remains a major public health challenge in sub-Saharan Africa, with pronounced spatial and temporal variation in transmission intensity that complicates effective control strategies. Accurate classification of transmission states is essential for guiding targeted interventions and strengthening early warning systems. This study develops a machine learning framework for the classification of malaria transmission states in Kenya using monthly panel data from 47 counties spanning the period 2015 to 2025. Transmission was categorised into four operationally relevant states based on incidence thresholds. Four supervised learning models, namely multinomial logistic regression, random fores

health informatics