Caregiver-infant interactions selectively shape emerging functional connectivity in the neonatal brain

From birth, human infants engage in multi-modal social exchanges with caregivers that involve the coordination of gaze and touch to guide attention and support neurodevelopment. However, little is known about the association between these first interactive experiences and the functional organization of the developing brain during the first postnatal month, a window of remarkable brain growth in humans. We address this gap by combining microanalytic coding of caregiver- infant interactions with task-free functional connectivity (FC), measured using high-density diffuse optical tomography (HD-DOT) in infants homes during the first postnatal month. Task-free FC measures the intrinsic functional