Tumor gene changes linked to shorter gallbladder cancer survival, analysis shows

Gallbladder cancer (GBC) is an extremely aggressive biliary tract malignancy characterized by silent early progression, late-stage diagnosis and poor prognosis. It is one of the most lethal gastrointestinal cancers, with a five-year survival rate often below 10%, partly because only about 10–20% of patients are eligible for curative surgical resection at diagnosis.