An X-linked long non-coding RNA, PTCHD1-AS , and the core features of autism

Nature, Published online: 13 May 2026; doi:10.1038/s41586-026-10515-6 PTCHD1-AS, which encodes a long non-coding RNA, is associated with the aetiology of autism spectrum disorder in humans through striatal molecular and circuit-level dysregulation.