研究关注：Dual MTHFD1/2 inhibitor induces tumor regression in vivo

## 事件概览

The MTHFD enzyme family is central to one-carbon metabolism, with MTHFD2 showing cancer-selective overexpression linked to poor prognosis. E...

## 核心信息

The MTHFD enzyme family is central to one-carbon metabolism, with MTHFD2 showing cancer-selective overexpression linked to poor prognosis. Emerging data also identify MTHFD1 as a therapeutic vulnerability in select tumors, supporting MTHFD-targeted drug development.

## 为什么值得关注

这条内容与 cancer 相关，可能影响科研选题、技术趋势判断或产业观察。BioDir 已根据来源、摘要长度、主题词和潜在影响给出 51 分的候选评分。

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