PLOS Biology journal Score 53

研究关注:The selfish ribosome

by Mart Krupovic, Eugene V. Koonin The ribosome is responsible for protein synthesis in all cells, and is the cell’s largest energy consumer...

## 事件概览

by Mart Krupovic, Eugene V. Koonin The ribosome is responsible for protein synthesis in all cells, and is the cell’s largest energy consumer...

## 核心信息

by Mart Krupovic, Eugene V. Koonin The ribosome is responsible for protein synthesis in all cells, and is the cell’s largest energy consumer. We propose that the ribosome originated as a mutualistic symbiont of an RNA-dependent RNA polymerase ribozyme, supplying peptides that enhanced replication. As life transitioned from the RNA to the RNA–protein world, autonomous replicators became irreversibly addicted to the ribosome for producing replication proteins. Subsequent evolution is construed as a ribosomal takeover, whereby the ribosome evolved to consume most of the cell’s resources, while other cellular componentry ensured the propagation of the ribosome, while being fully dependent

## 为什么值得关注

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cell biology