Lognormal firing rate distribution reveals prominent fluctuation-driven regime in spinal motor networks

When spinal circuits generate rhythmic movements it is important that the neuronal activity remains within stable bounds to avoid saturation and to preserve responsiveness. In what dynamical regime does the neuronal population operate in order to achieve this? Here, we simultaneously record from hundreds of neurons in lumbar spinal circuits and establish the neuronal fraction that operates within either a mean-driven or a fluctuation-driven regime during generation of multiple motor behaviors. We find a rich diversity of firing rates across the neuronal population as reflected in a lognormal distribution and demonstrate that half of the neurons spend at least 50% of the time in the fluctuati